It is contraindicated in patients with known hypersensitivity to Tadalafil and to any of its excipients. Administration of Tadalafil is also contraindicated in patients who are taking any form of organic nitrates as it is known to increase the hypotensive effects of the nitrate.
Torfil 2.5: Tadalafil is not recommended for concomitant use with guanylate cyclase (GC) stimulator due to potentiation of the hypotensive effects of GC stimulator.